| Rank | Rider | Rating | Time |
|---|---|---|---|
| 1 | #1 | 51:46 | |
| 2 | #2 | + 08 | |
| 3 | #11 | + 16 | |
| 4 | #4 | + 26 | |
| 5 | #7 | + 28 | |
| 6 | #8 | + 29 | |
| 7 | #17 | + 49 | |
| 8 | #3 | + 01:22 | |
| 9 | #5 | + 01:35 | |
| 10 | #18 | + 01:46 | |
| 11 | #13 | + 01:50 | |
| 12 | #6 | + 01:58 | |
| 13 | #12 | + 02:14 | |
| 14 | #15 | + 02:35 | |
| 15 | #20 | + 02:42 | |
| 16 | #39 | + 02:58 | |
| 17 | #22 | " | |
| 18 | #32 | + 03:03 | |
| 19 | #24 | + 03:04 | |
| 20 | #21 | + 03:19 | |
| 21 | #34 | + 03:27 | |
| 22 | #25 | + 03:42 | |
| 23 | #10 | + 03:52 | |
| 24 | #46 | + 04:04 | |
| 25 | #14 | + 04:14 | |
| 26 | #83 | + 04:27 | |
| 27 | #23 | + 04:41 | |
| 28 | #43 | + 05:09 | |
| 29 | #33 | + 05:26 | |
| 30 | #35 | + 05:41 | |
| 31 | #81 | + 06:02 | |
| 32 | #93 | + 06:03 | |
| 33 | #69 | + 06:45 | |
| 34 | #95 | + 07:27 | |
| 35 | #130 | + 08:08 | |
| 36 | #153 | + 08:29 | |
| 37 | #60 | + 00 | |
| 38 | #61 | " | |
| 39 | #240 | " | |
| 40 | #141 | " | |
| 41 | #191 | " | |
| 42 | #201 | " | |
| 43 | #157 | " | |
| 44 | #103 | " | |
| 45 | #282 | " | |
| DNF | #49 | ||
| DNF | #221 | ||
| DNS | #229 |
UCI Cyclo-cross World Cup 2021-2022
| 1 | - |  Lucinda Brand | 432 |
| 2 | - | Denise Betsema | 361 |
| 3 | - | Puck Pieterse | 350 |
| 4 | - | Fem van Empel | 315 |
| 5 | (1) | Marianne Vos | 254 |
Info
| Date | 13 October 2021 |
| Start |  Fayetteville |
| Finish | Fayetteville |
| Type | Individual Road Race |
Last winners
| 2021 | |
| 2019 |
Most wins