| Date | 06 March 2021 |
|---|---|
| Category | 1.UWT |
| Start | Siena |
| Finish | Siena |
| Distance | 184.0 km |
| Website | www.strade-bianche.it/en/ |
| 2021 | Mathieu van der Poel |
| 2020 | Wout Van Aert |
| 2019 | Julian Alaphilippe |
| 2018 | Tiesj Benoot |
| 2017 | Michal Kwiatkowski |
| 2016 | Fabian Cancellara |
| 2015 | Zdenek Stybar |
| 2014 | Michal Kwiatkowski |
| 2013 | Moreno Moser |
| 2012 | Fabian Cancellara |
| 3 | Fabian Cancellara |
| 2 | Michal Kwiatkowski |
| 2 | Tadej Pogacar |
| 1 | Maxim Iglinsky |
| 1 | Alexander Kolobnev |
| 1 | Zdenek Stybar |
| 1 | Moreno Moser |
| 1 | Julian Alaphilippe |
| 1 | Wout Van Aert |
| 1 | Mathieu van der Poel |